ELF5 modulates the estrogen receptor cistrome in breast cancer

Acquired resistance to endocrine therapy is responsible for half of the therapeutic failures in the treatment of breast cancer. Recent findings have implicated increased expression of the ETS transcription factor ELF5 as a potential modulator of estrogen action and driver of endocrine resistance, an...

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Veröffentlicht in:PLoS Genet
Hauptverfasser: Piggin, Catherine L., Roden, Daniel L., Law, Andrew M. K., Molloy, Mark P., Krisp, Christoph, Swarbrick, Alexander, Naylor, Matthew J., Kalyuga, Maria, Kaplan, Warren, Oakes, Samantha R., Gallego-Ortega, David, Clark, Susan J., Carroll, Jason S., Bartonicek, Nenad, Ormandy, Christopher J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2020
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6959601/
https://ncbi.nlm.nih.gov/pubmed/31895944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008531
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