A carregar...

Targeting cyclin-dependent kinase 1 (CDK1) but not CDK4/6 or CDK2 is selectively lethal to MYC-dependent human breast cancer cells

BACKGROUND: Although MYC is an attractive therapeutic target for breast cancer treatment, it has proven challenging to inhibit MYC directly, and clinically effective pharmaceutical agents targeting MYC are not yet available. An alternative approach is to identify genes that are synthetically lethal...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Kang, Jian, Sergio, C Marcelo, Sutherland, Robert L, Musgrove, Elizabeth A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3903446/
https://ncbi.nlm.nih.gov/pubmed/24444383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-32
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!