Pretreatment with a soluble activin type IIB receptor/Fc fusion protein improves hypoxia-induced muscle dysfunction

Por Pistilli, Emidio E., Bogdanovich, Sasha, Mosqueira, Matias, Lachey, Jennifer, Seehra, Jasbir, Khurana, Tejvir S.
Publicado em 2010

The bacterial cell-division protein ZipA and its interaction with an FtsZ fragment revealed by X-ray crystallography

Por Mosyak, Lidia, Zhang, Yan, Glasfeld, Elizabeth, Haney, Steve, Stahl, Mark, Seehra, Jasbir, Somers, William S.
Publicado em 2000

Targeting the Activin Type IIB Receptor to Improve Muscle Mass and Function in the mdx Mouse Model of Duchenne Muscular Dystrophy

Por Pistilli, Emidio E., Bogdanovich, Sasha, Goncalves, Marcus D., Ahima, Rexford S., Lachey, Jennifer, Seehra, Jasbir, Khurana, Tejvir
Publicado em 2011

SOLUBLE ACTIVIN RECEPTOR TYPE IIB INCREASES FORWARD PULLING TENSION IN THE MDX MOUSE

Por Carlson, C. George, Bruemmer, Kay, Sesti, Jenna, Stefanski, Casey, Curtis, Heather, Ucran, Jeffrey, Lachey, Jennifer, Seehra, Jasbir S.
Publicado em 2011

Inhibition of bone morphogenetic protein signaling reduces vascular calcification and atherosclerosis

Por Derwall, Matthias, Malhotra, Rajeev, Lai, Carol S, Beppu, Yuko, Aikawa, Elena, Seehra, Jasbir S., Zapol, Warren M, Bloch, Kenneth D., Yu, Paul B.
Publicado em 2012

Genetic and pharmacological targeting of activin receptor-like kinase 1 impairs tumor growth and angiogenesis

Por Cunha, Sara I., Pardali, Evangelia, Thorikay, Midory, Anderberg, Charlotte, Hawinkels, Lukas, Goumans, Marie-José, Seehra, Jasbir, Heldin, Carl-Henrik, ten Dijke, Peter, Pietras, Kristian
Publicado em 2010

Specificity and Structure of a High Affinity Activin Receptor-like Kinase 1 (ALK1) Signaling Complex

Por Townson, Sharon A., Martinez-Hackert, Erik, Greppi, Chloe, Lowden, Patricia, Sako, Dianne, Liu, June, Ucran, Jeffrey A., Liharska, Katia, Underwood, Kathryn W., Seehra, Jasbir, Kumar, Ravindra, Grinberg, Asya V.
Publicado em 2012

Inhibition of Activin Receptor Type IIB Increases Strength and Lifespan in Myotubularin-Deficient Mice

Por Lawlor, Michael W., Read, Benjamin P., Edelstein, Rachel, Yang, Nicole, Pierson, Christopher R., Stein, Matthew J., Wermer-Colan, Ariana, Buj-Bello, Anna, Lachey, Jennifer L., Seehra, Jasbir S., Beggs, Alan H.
Publicado em 2011

Soluble Endoglin Specifically Binds Bone Morphogenetic Proteins 9 and 10 via Its Orphan Domain, Inhibits Blood Vessel Formation, and Suppresses Tumor Growth

Por Castonguay, Roselyne, Werner, Eric D., Matthews, Robert G., Presman, Eleonora, Mulivor, Aaron W., Solban, Nicolas, Sako, Dianne, Pearsall, R. Scott, Underwood, Kathryn W., Seehra, Jasbir, Kumar, Ravindra, Grinberg, Asya V.
Publicado em 2011

A Novel Therapeutic Approach to Treating Obesity through Modulation of TGFβ Signaling

Por Koncarevic, Alan, Kajimura, Shingo, Cornwall-Brady, Milton, Andreucci, Amy, Pullen, Abigail, Sako, Dianne, Kumar, Ravindra, Grinberg, Asya V., Liharska, Katia, Ucran, Jeffrey A., Howard, Elizabeth, Spiegelman, Bruce M., Seehra, Jasbir, Lachey, Jennifer
Publicado em 2012

A soluble activin type IIA receptor induces bone formation and improves skeletal integrity

Por Pearsall, R. Scott, Canalis, Ernesto, Cornwall-Brady, Milton, Underwood, Kathryn W., Haigis, Brendan, Ucran, Jeffrey, Kumar, Ravindra, Pobre, Eileen, Grinberg, Asya, Werner, Eric D., Glatt, Vaida, Stadmeyer, Lisa, Smith, Deanna, Seehra, Jasbir, Bouxsein, Mary L.
Publicado em 2008

A soluble bone morphogenetic protein type IA receptor increases bone mass and bone strength

Por Baud’huin, Marc, Solban, Nicolas, Cornwall-Brady, Milton, Sako, Dianne, Kawamoto, Yoshimi, Liharska, Katia, Lath, Darren, Bouxsein, Mary L., Underwood, Kathryn W., Ucran, Jeffrey, Kumar, Ravindra, Pobre, Eileen, Grinberg, Asya, Seehra, Jasbir, Canalis, Ernesto, Pearsall, R. Scott, Croucher, Peter I.
Publicado em 2012

Characterization of the Ligand Binding Functionality of the Extracellular Domain of Activin Receptor Type IIB

Por Sako, Dianne, Grinberg, Asya V., Liu, June, Davies, Monique V., Castonguay, Roselyne, Maniatis, Silas, Andreucci, Amy J., Pobre, Eileen G., Tomkinson, Kathleen N., Monnell, Travis E., Ucran, Jeffrey A., Martinez-Hackert, Erik, Pearsall, R. Scott, Underwood, Kathryn W., Seehra, Jasbir, Kumar, Ravindra
Publicado em 2010

Meteorin-like is a hormone that regulates immune-adipose interactions to increase beige fat thermogenesis

Por Rao, Rajesh R., Long, Jonathan Z., White, James P., Svensson, Katrin J., Lou, Jesse, Lokurkar, Isha, Jedrychowski, Mark P., Ruas, Jorge L., Wrann, Christiane D., Lo, James C., Camera, Donny M., Lachey, Jenn, Gygi, Steven, Seehra, Jasbir, Hawley, John A., Spiegelman, Bruce M.
Publicado em 2014

Activin A promotes multiple myeloma-induced osteolysis and is a promising target for myeloma bone disease

Por Vallet, Sonia, Mukherjee, Siddhartha, Vaghela, Nileshwari, Hideshima, Teru, Fulciniti, Mariateresa, Pozzi, Samantha, Santo, Loredana, Cirstea, Diana, Patel, Kishan, Sohani, Aliyah R., Guimaraes, Alex, Xie, Wanling, Chauhan, Dharminder, Schoonmaker, Jesse A., Attar, Eyal, Churchill, Michael, Weller, Edie, Munshi, Nikhil, Seehra, Jasbir S., Weissleder, Ralph, Anderson, Kenneth C., Scadden, David T., Raje, Noopur
Publicado em 2010

Inhibition of bone morphogenetic protein signaling attenuates anemia associated with inflammation

Por Steinbicker, Andrea U., Sachidanandan, Chetana, Vonner, Ashley J., Yusuf, Rushdia Z., Deng, Donna Y., Lai, Carol S., Rauwerdink, Kristen M., Winn, Julia C., Saez, Borja, Cook, Colleen M., Szekely, Brian A., Roy, Cindy N., Seehra, Jasbir S., Cuny, Gregory D., Scadden, David T., Peterson, Randall T., Bloch, Kenneth D., Yu, Paul B.
Publicado em 2011