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Inhibition of bone morphogenetic protein signaling reduces vascular calcification and atherosclerosis
OBJECTIVE: The expression of bone morphogenetic proteins (BMPs) is enhanced in human atherosclerotic and calcific vascular lesions. While genetic gain- and loss-of-function experiments in mice have supported a causal role of BMP signaling in atherosclerosis and vascular calcification, it remains unc...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3679546/ https://ncbi.nlm.nih.gov/pubmed/22223731 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.111.242594 |
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