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Inhibition of Bone Morphogenetic Proteins Protects against Atherosclerosis and Vascular Calcification

RATIONALE: The bone morphogenetic proteins (BMP), a family of morphogens, have been implicated as mediators of calcification and inflammation in the vascular wall. OBJECTIVE: To investigate the effect of altered expression of Matrix Gla Protein (MGP), an inhibitor of BMP, on vascular disease. METHOD...

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Detalhes bibliográficos
Main Authors: Yao, Yucheng, Bennett, Brian J., Wang, Xuping, Rosenfeld, Michael E., Giachelli, Cecilia, Lusis, Aldons J., Boström, Kristina I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2994650/
https://ncbi.nlm.nih.gov/pubmed/20576934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.110.219071
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