Deletion of the Sequence Encoding the Tail Domain of the Bone Morphogenetic Protein type 2 Receptor Reveals a Bone Morphogenetic Protein 7-Specific Gain of Function

The bone morphogenetic protein (BMP) type II receptor (BMPR2) has a long cytoplasmic tail domain whose function is incompletely elucidated. Mutations in the tail domain of BMPR2 are found in familial cases of pulmonary arterial hypertension. To investigate the role of the tail domain of BMPR2 in BMP...

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Bibliografski detalji
Glavni autori: Leyton, Patricio A., Beppu, Hideyuki, Pappas, Alexandra, Martyn, Trejeeve M., Derwall, Matthias, Baron, David M., Galdos, Rita, Bloch, Donald B., Bloch, Kenneth D.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3792867/
https://ncbi.nlm.nih.gov/pubmed/24116187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076947
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