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Inhibition of bone morphogenetic protein signaling reduces vascular calcification and atherosclerosis

OBJECTIVE: The expression of bone morphogenetic proteins (BMPs) is enhanced in human atherosclerotic and calcific vascular lesions. While genetic gain- and loss-of-function experiments in mice have supported a causal role of BMP signaling in atherosclerosis and vascular calcification, it remains unc...

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Detaylı Bibliyografya
Asıl Yazarlar: Derwall, Matthias, Malhotra, Rajeev, Lai, Carol S, Beppu, Yuko, Aikawa, Elena, Seehra, Jasbir S., Zapol, Warren M, Bloch, Kenneth D., Yu, Paul B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3679546/
https://ncbi.nlm.nih.gov/pubmed/22223731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.111.242594
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