Inhibition of Activin Receptor Type IIB Increases Strength and Lifespan in Myotubularin-Deficient Mice

X-linked myotubular myopathy (XLMTM) is a congenital disorder caused by deficiency of the lipid phosphatase, myotubularin. Patients with XLMTM often have severe perinatal weakness that requires mechanical ventilation to prevent death from respiratory failure. Muscle biopsy specimens from patients wi...

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Detalhes bibliográficos
Main Authors: Lawlor, Michael W., Read, Benjamin P., Edelstein, Rachel, Yang, Nicole, Pierson, Christopher R., Stein, Matthew J., Wermer-Colan, Ariana, Buj-Bello, Anna, Lachey, Jennifer L., Seehra, Jasbir S., Beggs, Alan H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2011
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069865/
https://ncbi.nlm.nih.gov/pubmed/21281811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2010.10.035
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