Inhibition of Activin Receptor Type IIB Increases Strength and Lifespan in Myotubularin-Deficient Mice

X-linked myotubular myopathy (XLMTM) is a congenital disorder caused by deficiency of the lipid phosphatase, myotubularin. Patients with XLMTM often have severe perinatal weakness that requires mechanical ventilation to prevent death from respiratory failure. Muscle biopsy specimens from patients wi...

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Dades bibliogràfiques
Autors principals: Lawlor, Michael W., Read, Benjamin P., Edelstein, Rachel, Yang, Nicole, Pierson, Christopher R., Stein, Matthew J., Wermer-Colan, Ariana, Buj-Bello, Anna, Lachey, Jennifer L., Seehra, Jasbir S., Beggs, Alan H.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2011
Matèries:
Regular Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069865/
https://ncbi.nlm.nih.gov/pubmed/21281811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2010.10.035
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