Differential Muscle Hypertrophy Is Associated with Satellite Cell Numbers and Akt Pathway Activation Following Activin Type IIB Receptor Inhibition in Mtm1 p.R69C Mice

X-linked myotubular myopathy is a congenital myopathy caused by deficiency of myotubularin. Patients often present with severe perinatal weakness, requiring mechanical ventilation to prevent death from respiratory failure. We recently reported that an activin receptor type IIB inhibitor produced hyp...

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Detalhes bibliográficos
Main Authors: Lawlor, Michael W., Viola, Marissa G., Meng, Hui, Edelstein, Rachel V., Liu, Fujun, Yan, Ke, Luna, Elizabeth J., Lerch-Gaggl, Alexandra, Hoffmann, Raymond G., Pierson, Christopher R., Buj-Bello, Anna, Lachey, Jennifer L., Pearsall, Scott, Yang, Lin, Hillard, Cecilia J., Beggs, Alan H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2014
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4044712/
https://ncbi.nlm.nih.gov/pubmed/24726641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2014.03.003
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