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Administration of a soluble activin type IIB receptor promotes skeletal muscle growth independent of fiber type

This is the first report that inhibition of negative regulators of skeletal muscle by a soluble form of activin type IIB receptor (ACE-031) increases muscle mass independent of fiber-type expression. This finding is distinct from the effects of selective pharmacological inhibition of myostatin (GDF-...

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Bibliografische gegevens
Hoofdauteurs: Cadena, Samuel M., Tomkinson, Kathleen N., Monnell, Travis E., Spaits, Matthew S., Kumar, Ravindra, Underwood, Kathryn W., Pearsall, R. Scott, Lachey, Jennifer L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Physiological Society 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944638/
https://ncbi.nlm.nih.gov/pubmed/20466801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00866.2009
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