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Skeletal Response to Soluble Activin Receptor Type IIB in Mouse Models of Osteogenesis Imperfecta

Osteogenesis imperfecta (OI) is a heritable connective tissue disorder primarily due to mutations in the type I collagen genes (COL1A1 and COL1A2), leading to compromised biomechanical integrity in type I collagen containing tissues such as bone. Bone is inherently mechanosensitive and thus responds...

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Detalhes bibliográficos
Publicado no:J Bone Miner Res
Main Authors: Jeong, Youngjae, Daghlas, Salah A., Yixia, Xie, Hulbert, Molly A, Pfeiffer, Ferris M., Dallas, Mark R., Omosule, Catherine L., Pearsall, R. Scott, Dallas, Sarah L., Phillips, Charlotte L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6400483/
https://ncbi.nlm.nih.gov/pubmed/29813187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.3473
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