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Skeletal Response to Soluble Activin Receptor Type IIB in Mouse Models of Osteogenesis Imperfecta
Osteogenesis imperfecta (OI) is a heritable connective tissue disorder primarily due to mutations in the type I collagen genes (COL1A1 and COL1A2), leading to compromised biomechanical integrity in type I collagen containing tissues such as bone. Bone is inherently mechanosensitive and thus responds...
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| 發表在: | J Bone Miner Res |
|---|---|
| Main Authors: | , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6400483/ https://ncbi.nlm.nih.gov/pubmed/29813187 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.3473 |
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