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Soluble activin receptor type IIB decoy receptor differentially impacts murine osteogenesis imperfecta muscle function

INTRODUCTION: Osteogenesis imperfecta (OI) is characterized by skeletal fragility and muscle weakness. We investigated the effects of soluble activin type IIB receptor (sActRIIB-mFc) on muscle mass and function in two distinct mouse models of OI, osteogenesis imperfecta murine (oim) and +/G610C mous...

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Detalhes bibliográficos
Publicado no:Muscle Nerve
Main Authors: Jeong, Youngjae, Daghlas, Salah A., Kahveci, Alp S., Salamango, Daniel, Gentry, Bettina A., Brown, Marybeth, Rector, R. Scott, Pearsall, R. Scott, Phillips, Charlotte L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5702601/
https://ncbi.nlm.nih.gov/pubmed/28555931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mus.25706
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