Expression of the Rho-GEF Pbl/ECT2 is regulated by the UBE3A E3 ubiquitin ligase

Por Reiter, Lawrence T., Seagroves, Tiffany N., Bowers, Megan, Bier, Ethan
Publicado em 2006

Putative role of HIF transcriptional activity in melanocytes and melanoma biology

Por Zbytek, Blazej, Peacock, Danielle L., Seagroves, Tiffany N., Slominski, Andrzej
Publicado em 2013

Chemoprevention Activity of Dipyridamole in the MMTV-PyMT Transgenic Mouse Model of Breast Cancer

Por Wang, Chunmei, Schwab, Luciana P., Fan, Meiyun, Seagroves, Tiffany N., Buolamwini, John K.
Publicado em 2013

Anti-matrix metalloproteinase-9 DNAzyme decreases tumor growth in the MMTV-PyMT mouse model of breast cancer

Por Hallett, Miranda A, Teng, Bin, Hasegawa, Hisashi, Schwab, Luciana P, Seagroves, Tiffany N, Pourmotabbed, Tayebeh
Publicado em 2013

SMARCE1 regulates metastatic potential of breast cancer cells through the HIF1A/PTK2 pathway

Por Sethuraman, Aarti, Brown, Martin, Seagroves, Tiffany N., Wu, Zhao-Hui, Pfeffer, Lawrence M., Fan, Meiyun
Publicado no Breast Cancer Res (2016)

Bisphenol A Induces Sox2 in ER(+) Breast Cancer Stem-Like Cells

Por Lillo, M. Angeles, Nichols, Cydney, Seagroves, Tiffany N., Miranda-Carboni, Gustavo A., Krum, Susan A.
Publicado no Horm Cancer (2017)

Hypoxia-inducible Factor-1α Induces ErbB4 Signaling in the Differentiating Mammary Gland

Por Paatero, Ilkka, Seagroves, Tiffany N., Vaparanta, Katri, Han, Wen, Jones, Frank E., Johnson, Randall S., Elenius, Klaus
Publicado em 2014

C/EBPβ, but not C/EBPα, is essential for ductal morphogenesis, lobuloalveolar proliferation, and functional differentiation in the mouse mammary gland

Por Seagroves, Tiffany N., Krnacik, Susanne, Raught, Brian, Gay, Jason, Burgess-Beusse, Bonnie, Darlington, Gretchen J., Rosen, Jeffrey M.
Publicado em 1998

MicroRNA-18a inhibits hypoxia-inducible factor 1α activity and lung metastasis in basal breast cancers

Por Krutilina, Raisa, Sun, Wenlin, Sethuraman, Aarti, Brown, Martin, Seagroves, Tiffany N, Pfeffer, Lawrence M, Ignatova, Tatyana, Fan, Meiyun
Publicado no Breast Cancer Res (2014)

Transcription Factor HIF-1 Is a Necessary Mediator of the Pasteur Effect in Mammalian Cells

Por Seagroves, Tiffany N., Ryan, Heather E., Lu, Han, Wouters, Bradly G., Knapp, Merrill, Thibault, Pierre, Laderoute, Keith, Johnson, Randall S.
Publicado em 2001

mTOR/MYC Axis Regulates O-GlcNAc Transferase (OGT) Expression and O-GlcNAcylation in Breast Cancer

Por Sodi, Valerie L., Khaku, Sakina, Krutilina, Raisa, Schwab, Luciana P., Vocadlo, David J., Seagroves, Tiffany N., Reginato, Mauricio J.
Publicado no Mol Cancer Res (2015)

The Oncogene HER2/neu (ERBB2) Requires the Hypoxia-inducible Factor HIF-1 for Mammary Tumor Growth and Anoikis Resistance

Por Whelan, Kelly A., Schwab, Luciana P., Karakashev, Sergey V., Franchetti, Lisa, Johannes, Gregg J., Seagroves, Tiffany N., Reginato, Mauricio J.
Publicado em 2013

Assessment of the Tumorigenic Potential of Spontaneously Immortalized and hTERT-Immortalized Cultured Dental Pulp Stem Cells

Por Wilson, Ryan, Urraca, Nora, Skobowiat, Cezary, Hope, Kevin A., Miravalle, Leticia, Chamberlin, Reed, Donaldson, Martin, Seagroves, Tiffany N., Reiter, Lawrence T.
Publicado no Stem Cells Transl Med (2015)

VHL Deletion Impairs Mammary Alveologenesis but Is Not Sufficient for Mammary Tumorigenesis

Por Seagroves, Tiffany N., Peacock, Danielle L., Liao, Debbie, Schwab, Luciana P., Krueger, Robin, Handorf, Charles R., Haase, Volker H., Johnson, Randall S.
Publicado em 2010

Benzimidazole Analogs as Potent Hypoxia Inducible Factor Inhibitors: Synthesis, Biological Evaluation, and Profiling Drug-like Properties

Por Chen, Jianjun, Wang, Jin, Schwab, Luciana P., Park, Kyung-Tae, Seagroves, Tiffany N., Jennings, Lisa K., Miller, Duane D., Li, Wei
Publicado no Anticancer Res (2014)

Methylparaben stimulates tumor initiating cells in ER+ breast cancer models

Por Osuna, Maria Angeles Lillo, Nichols, Cydney, Perry, Chanel, Runke, Stephanie, Krutilina, Raisa, Seagroves, Tiffany N., Miranda-Carboni, Gustavo A., Krum, Susan A.
Publicado no J Appl Toxicol (2016)

Hypoxia-inducible factor 1α promotes primary tumor growth and tumor-initiating cell activity in breast cancer

Por Schwab, Luciana P, Peacock, Danielle L, Majumdar, Debeshi, Ingels, Jesse F, Jensen, Laura C, Smith, Keisha D, Cushing, Richard C, Seagroves, Tiffany N
Publicado em 2012

O-GlcNAcylation regulates cancer metabolism and survival stress signaling via regulation of HIF-1 pathway

Por Ferrer, Christina M., Lynch, Thomas P., Sodi, Valerie L., Falcone, John N., Schwab, Luciana P., Peacock, Danielle L., Vocadlo, David J., Seagroves, Tiffany N., Reginato, Mauricio J.
Publicado em 2014

Breast Tumor Kinase (Brk/PTK6) is Induced by HIF, Glucocorticoid Receptor and PELP1 Mediated Stress Signaling in Triple-Negative Breast Cancer

Por Anderson, Tarah M Regan, Ma, Shihong, Raj, Ganesh V, Cidlowski, John A, Helle, Taylor M, Knutson, Todd P, Krutilina, Raisa I, Seagroves, Tiffany N, Lange, Carol A
Publicado no Cancer Res (2016)

ITGA6 is directly regulated by hypoxia-inducible factors and enriches for cancer stem cell activity and invasion in metastatic breast cancer models

Por Brooks, Danielle L. Peacock, Schwab, Luciana P., Krutilina, Raisa, Parke, Deanna N., Sethuraman, Aarti, Hoogewijs, David, Schörg, Alexandra, Gotwald, Lauren, Fan, Meiyun, Wenger, Roland H., Seagroves, Tiffany N.
Publicado no Mol Cancer (2016)