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Hypoxia-inducible Factor-1α Induces ErbB4 Signaling in the Differentiating Mammary Gland
Conditional knock-out of Hif1a in the mouse mammary gland impairs lobuloalveolar differentiation during lactation. Here, we demonstrate that expression of ErbB4 was reduced in the lobulalveoli of mice with mammary gland-specific deletion of Hif1a. Erbb4 was not, however, a direct target gene for tra...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4139252/ https://ncbi.nlm.nih.gov/pubmed/24966332 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.533497 |
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