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The Intracellular Domain of ErbB4 Induces Differentiation of Mammary Epithelial Cells

Differentiation of mammary epithelium in vivo requires signaling through prolactin- and ErbB4/HER4-dependent mechanisms; how these pathways intersect is unknown. We show herein that HC11 mouse mammary cells undergo ErbB4-dependent lactational differentiation. Prolactin and the ErbB4 ligand HB-EGF ea...

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Detalhes bibliográficos
Main Authors: Muraoka-Cook, Rebecca S., Sandahl, Melissa, Husted, Carty, Hunter, Debra, Miraglia, Leah, Feng, Shu-mang, Elenius, Klaus, Earp, H. Shelton
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1556387/
https://ncbi.nlm.nih.gov/pubmed/16837552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-02-0101
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