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HER4 D-box sequences regulate mitotic progression and degradation of the nuclear HER4 cleavage product, s80(HER4)
Heregulin-mediated activation of HER4 initiates receptor cleavage (releasing an 80-kDa HER4 intracellular domain, s80(HER4), containing nuclear localization sequences) and results in G2/M delay by unknown signaling mechanisms. We report herein that s80(HER4) contains a functional cyclin B-like seque...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2007
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2917069/ https://ncbi.nlm.nih.gov/pubmed/17638867 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-06-4145 |
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