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ErbB4 tyrosine kinase inhibition impairs neuromuscular development in zebrafish embryos

Tyrosine kinase inhibitors are widely used in the clinic, but limited information is available about their toxicity in developing organisms. Here, we tested the effect of tyrosine kinase inhibitors targeting the ErbB receptors for their effects on developing zebrafish (Danio rerio) embryos. Embryos...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Paatero, Ilkka, Veikkolainen, Ville, Mäenpää, Matias, Schmelzer, Etienne, Belting, Heinz-Georg, Pelliniemi, Lauri J., Elenius, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6589560/
https://ncbi.nlm.nih.gov/pubmed/30462579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E18-07-0460
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