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ErbB4 tyrosine kinase inhibition impairs neuromuscular development in zebrafish embryos

Tyrosine kinase inhibitors are widely used in the clinic, but limited information is available about their toxicity in developing organisms. Here, we tested the effect of tyrosine kinase inhibitors targeting the ErbB receptors for their effects on developing zebrafish (Danio rerio) embryos. Embryos...

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Détails bibliographiques
Publié dans:Mol Biol Cell
Auteurs principaux: Paatero, Ilkka, Veikkolainen, Ville, Mäenpää, Matias, Schmelzer, Etienne, Belting, Heinz-Georg, Pelliniemi, Lauri J., Elenius, Klaus
Format: Artigo
Langue:Inglês
Publié: The American Society for Cell Biology 2019
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6589560/
https://ncbi.nlm.nih.gov/pubmed/30462579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E18-07-0460
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