ITGA6 is directly regulated by hypoxia-inducible factors and enriches for cancer stem cell activity and invasion in metastatic breast cancer models

BACKGROUND: Hypoxia-inducible factors (HIFs) are well-established mediators of tumor growth, the epithelial to mesenchymal transition (EMT) and metastasis. In several types of solid tumors, including breast cancers, the HIFs play a critical role in maintaining cancer stem cell (CSC) activity. Thus,...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Mol Cancer
Asıl Yazarlar: Brooks, Danielle L. Peacock, Schwab, Luciana P., Krutilina, Raisa, Parke, Deanna N., Sethuraman, Aarti, Hoogewijs, David, Schörg, Alexandra, Gotwald, Lauren, Fan, Meiyun, Wenger, Roland H., Seagroves, Tiffany N.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2016
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4802728/
https://ncbi.nlm.nih.gov/pubmed/27001172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-016-0510-x
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller