Breast tumor kinase (Brk/PTK6) is a mediator of hypoxia-associated breast cancer progression

Basal-type triple-negative breast cancers (TNBC) are aggressive and difficult to treat relative to luminal type breast cancers. TNBC often express abundant Met receptors and are enriched for transcriptional targets regulated by hypoxia inducible factor 1-alpha (HIF-1α), which independently predicts...

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Hauptverfasser: Regan Anderson, Tarah M., Peacock, Danielle L., Daniel, Andrea R., Hubbard, Gregory K., Lofgren, Kristopher A., Girard, Brian J., Schörg, Alexandra, Hoogewijs, David, Wenger, Roland H., Seagroves, Tiffany N., Lange, Carol A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3820501/
https://ncbi.nlm.nih.gov/pubmed/23928995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-0523
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