Mammary gland specific expression of Brk/PTK6 promotes delayed involution and tumor formation associated with activation of p38 MAPK

INTRODUCTION: Protein tyrosine kinases (PTKs) are frequently overexpressed and/or activated in human malignancies, and regulate cancer cell proliferation, cellular survival, and migration. As such, they have become promising molecular targets for new therapies. The non-receptor PTK termed breast tum...

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Main Authors: Lofgren, Kristopher A, Ostrander, Julie H, Housa, Daniel, Hubbard, Gregory K, Locatelli, Alessia, Bliss, Robin L, Schwertfeger, Kathryn L, Lange, Carol A
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262201/
https://ncbi.nlm.nih.gov/pubmed/21923922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2946
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