Model systems for studying cellular mechanisms of SCN1A-related epilepsy

af Schutte, Soleil S., Schutte, Ryan J., Barragan, Eden V., O'Dowd, Diane K.
Udgivet i J Neurophysiol (2016)

Astrocyte-enriched feeder layers from cryopreserved cells support differentiation of spontaneously active networks of human iPSC-derived neurons

af Schutte, Ryan J., Xie, Yunyao, Ng, Nathan N., Figueroa, Priscilla, Pham, An T., O’Dowd, Diane K.
Udgivet i J Neurosci Methods (2017)

A Knock-In Model of Human Epilepsy in Drosophila Reveals a Novel Cellular Mechanism Associated with Heat-Induced Seizure

af Sun, Lei, Gilligan, Jeff, Staber, Cynthia, Schutte, Ryan J., Nguyen, Vivian, O'Dowd, Diane K., Reenan, Robert
Udgivet 2012

Reproducible and efficient generation of functionally active neurons from human hiPSCs for preclinical disease modeling

af Xie, Yunyao, Schutte, Ryan J., Ng, Nathan N., Ess, Kevin C., Schwartz, Philip H., O’Dowd, Diane K.
Udgivet i Stem Cell Res (2017)

Oncogenic PKC-ι activates Vimentin during epithelial-mesenchymal transition in melanoma; a study based on PKC-ι and PKC-ζ specific inhibitors

af Ratnayake, Wishrawana S., Apostolatos, Christopher A., Apostolatos, André H., Schutte, Ryan J., Huynh, Monica A., Ostrov, David A., Acevedo-Duncan, Mildred
Udgivet i Cell Adh Migr (2018)

Structural Elements Recognized by Abacavir-Induced T Cells

af Yerly, Daniel, Pompeu, Yuri Andreiw, Schutte, Ryan J., Eriksson, Klara. K., Strhyn, Anette, Bracey, Austin. W., Buus, Soren, Ostrov, David A.
Udgivet i Int J Mol Sci (2017)

A Novel Small Molecule Inhibits Intrahepatocellular Accumulation of Z-Variant Alpha 1-Antitrypsin In Vitro and In Vivo

af Zhang, Xiaojuan, Pham, Kien, Li, Danmeng, Schutte, Ryan J., Gonzalo, David Hernandez, Zhang, Penghui, Oshins, Regina, Tan, Weihong, Brantly, Mark, Liu, Chen, Ostrov, David A.
Udgivet i Cells (2019)

Knock-in model of Dravet syndrome reveals a constitutive and conditional reduction in sodium current

af Schutte, Ryan J., Schutte, Soleil S., Algara, Jacqueline, Barragan, Eden V., Gilligan, Jeff, Staber, Cynthia, Savva, Yiannis A., Smith, Martin A., Reenan, Robert, O'Dowd, Diane K.
Udgivet 2014

The role of HLA- A *33:01 in Patients with Cholestatic Hepatitis attributed to Terbinafine

af Fontana, Robert John, Cirulli, Elizabeth Theresa, Gu, Jiezhun, Kleiner, David, Ostrov, David, Phillips, Elizabeth, Schutte, Ryan, Barnhart, Huiman, Chalasani, Naga, Watkins, Paul Brent, Hoofnagle, Jay H.
Udgivet i J Hepatol (2018)

HLA-B*14:01 and HLA-B*35:01 are associated with trimethoprim-sulfamethoxazole induced liver injury

af Li, Yi-Ju, Phillips, Elizabeth, Dellinger, Andrew, Nicoletti, Paola, Schutte, Ryan, Li, Danmeng, Ostrov, David A., Fontana, Robert J., Watkins, Paul B., Stolz, Andrew, Daly, Ann K, Aithal, Guruprasad P, Barnhart, Huiman, Chalasani, Naga
Udgivet i Hepatology (2021)

Identification of drug-specific public TCR driving severe cutaneous adverse reactions

af Pan, Ren-You, Chu, Mu-Tzu, Wang, Chuang-Wei, Lee, Yun-Shien, Lemonnier, Francois, Michels, Aaron W., Schutte, Ryan, Ostrov, David A., Chen, Chun-Bing, Phillips, Elizabeth Jane, Mallal, Simon Alexander, Mockenhaupt, Maja, Bellón, Teresa, Tassaneeyakul, Wichittra, White, Katie D., Roujeau, Jean-Claude, Chung, Wen-Hung, Hung, Shuen-Iu
Udgivet i Nat Commun (2019)

Shared peptide binding of HLA Class I and II alleles associate with cutaneous nevirapine hypersensitivity and identify novel risk alleles

af Pavlos, Rebecca, McKinnon, Elizabeth J., Ostrov, David A., Peters, Bjoern, Buus, Soren, Koelle, David, Chopra, Abha, Schutte, Ryan, Rive, Craig, Redwood, Alec, Restrepo, Susana, Bracey, Austin, Kaever, Thomas, Myers, Paisley, Speers, Ellen, Malaker, Stacy A., Shabanowitz, Jeffrey, Jing, Yuan, Gaudieri, Silvana, Hunt, Donald F., Carrington, Mary, Haas, David W., Mallal, Simon, Phillips, Elizabeth J.
Udgivet i Sci Rep (2017)

HLA-A*32:01 is strongly associated with vancomycin-induced drug reaction with eosinophilia and systemic symptoms

af Konvinse, Katherine C, Trubiano, Jason A, Pavlos, Rebecca, James, Ian, Shaffer, Christian M, Bejan, Cosmin A, Schutte, Ryan J, Ostrov, David A, Pilkinton, Mark A, Rosenbach, Misha, Zwerner, Jeffrey P, Williams, Kristina B, Bourke, Jack, Martinez, Patricia, Rwandamuriye, Francois, Chopra, Abha, Watson, Mark, Redwood, Alec J, White, Katie D, Mallal, Simon A, Phillips, Elizabeth J
Udgivet i J Allergy Clin Immunol (2019)