Oncogenic PKC-ι activates Vimentin during epithelial-mesenchymal transition in melanoma; a study based on PKC-ι and PKC-ζ specific inhibitors

Melanoma is one of the fastest growing cancers in the United States and is accompanied with a poor prognosis owing to tumors being resistant to most therapies. Atypical protein kinase Cs (aPKC) are involved in malignancy in many cancers. We previously reported that aPKCs play a key role in melanoma&...

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Publicado en:Cell Adh Migr
Autores principales: Ratnayake, Wishrawana S., Apostolatos, Christopher A., Apostolatos, André H., Schutte, Ryan J., Huynh, Monica A., Ostrov, David A., Acevedo-Duncan, Mildred
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2018
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Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6363030/
https://ncbi.nlm.nih.gov/pubmed/29781749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336918.2018.1471323
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