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Inhibition of atypical protein kinase C-ι effectively reduces the malignancy of prostate cancer cells by downregulating the NF-κB signaling cascade

Prostate cancer (PC) is the most common type of cancer among men. Aggressive and metastatic PC results in life- threatening tumors, and represents one of the leading causes of mortality in men. Previous studies of atypical protein kinase C isoforms (aPKCs) have highlighted its role in the survival o...

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Bibliographic Details
Published in:Int J Oncol
Main Authors: Apostolatos, André H., Ratnayake, Wishrawana S., Win-Piazza, Hla, Apostolatos, Christopher A., Smalley, Tracess, kang, Loveleen, Salup, Raoul, Hill, Robert, Acevedo-Duncan, Mildred
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6192717/
https://ncbi.nlm.nih.gov/pubmed/30226591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2018.4542
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