Gene Therapies for Neovascular Age-Related Macular Degeneration

od Pechan, Peter, Wadsworth, Samuel, Scaria, Abraham
Izdano u Cold Spring Harb Perspect Med (2015)

Mutations within the ADP (E3-11.6K) Protein Alter Processing and Localization of ADP and the Kinetics of Cell Lysis of Adenovirus-Infected Cells

od Tollefson, Ann E., Scaria, Abraham, Ying, Baoling, Wold, William S. M.
Izdano 2003

Aurintricarboxylic acid increases yield of HSV-1 vectors

od Pechan, Peter, Ardinger, Jeffery, Ketavarapu, Jyothi, Rubin, Hillard, Wadsworth, Samuel C, Scaria, Abraham
Izdano u Mol Ther Methods Clin Dev (2014)

CRISPR/Cas9-Mediated Genome Editing as a Therapeutic Approach for Leber Congenital Amaurosis 10

od Ruan, Guo-Xiang, Barry, Elizabeth, Yu, Dan, Lukason, Michael, Cheng, Seng H., Scaria, Abraham
Izdano u Mol Ther (2017)

Cytotoxic T Lymphocyte Responses to Transgene Product, Not Adeno-Associated Viral Capsid Protein, Limit Transgene Expression in Mice

od Siders, William M., Shields, Jacqueline, Kaplan, Johanne, Lukason, Michael, Woodworth, Lisa, Wadsworth, Sam, Scaria, Abraham
Izdano 2009

Adenovirus-Mediated Persistent Cystic Fibrosis Transmembrane Conductance Regulator Expression in Mouse Airway Epithelium

od Scaria, Abraham, St. George, Judith A., Jiang, Canwen, Kaplan, Johanne M., Wadsworth, Samuel C., Gregory, Richard J.
Izdano 1998

Inhibition of pathological brain angiogenesis through systemic delivery of AAV vector expressing soluble FLT1

od Shen, Fanxia, Mao, Lei, Zhu, Wan, Lawton, Michael T., Pechan, Peter, Colosi, Peter, Wu, Zhijian, Scaria, Abraham, Su, Hua
Izdano u Gene Ther (2015)

Novel Role for E4 Region Genes in Protection of Adenovirus Vectors from Lysis by Cytotoxic T Lymphocytes

od Kaplan, Johanne M., Armentano, Donna, Scaria, Abraham, Woodworth, Lisa A., Pennington, Sarah E., Wadsworth, Samuel C., Smith, Alan E., Gregory, Richard J.
Izdano 1999

AAV5-mediated sFLT01 gene therapy arrests retinal lesions in Ccl2(−/−) /Cx3cr1(−)(/)(−) mice

od Tuo, Jingsheng, Pang, Ji-Jing, Cao, Xiaoguang, Shen, Defen, Zhang, Jun, Scaria, Abraham, Wadsworth, Samuel C., Pechan, Peter, Boye, Sanford L., Hauswirth, William W., Chan, Chi-Chao
Izdano 2011

Inhibition of Choroidal Neovascularization in a Nonhuman Primate Model by Intravitreal Administration of an AAV2 Vector Expressing a Novel Anti-VEGF Molecule

od Lukason, Michael, DuFresne, Elizabeth, Rubin, Hillard, Pechan, Peter, Li, Qiuhong, Kim, Ivana, Kiss, Szilard, Flaxel, Christina, Collins, Margaret, Miller, Joan, Hauswirth, William, MacLachlan, Timothy, Wadsworth, Samuel, Scaria, Abraham
Izdano 2011

Universal Method for the Purification of Recombinant AAV Vectors of Differing Serotypes

od Nass, Shelley A., Mattingly, Maryellen A., Woodcock, Denise A., Burnham, Brenda L., Ardinger, Jeffrey A., Osmond, Shayla E., Frederick, Amy M., Scaria, Abraham, Cheng, Seng H., O’Riordan, Catherine R.
Izdano u Mol Ther Methods Clin Dev (2017)

Preclinical Safety Evaluation of AAV2-sFLT01— A Gene Therapy for Age-related Macular Degeneration

od MacLachlan, Timothy K, Lukason, Michael, Collins, Margaret, Munger, Robert, Isenberger, Elisabete, Rogers, Cindy, Malatos, Shana, DuFresne, Elizabeth, Morris, James, Calcedo, Roberto, Veres, Gabor, Scaria, Abraham, Andrews, Laura, Wadsworth, Samuel
Izdano 2011

Interleukin-17 Retinotoxicity Is Prevented by Gene Transfer of a Soluble Interleukin-17 Receptor Acting as a Cytokine Blocker: Implications for Age-Related Macular Degeneration

od Ardeljan, Daniel, Wang, Yujuan, Park, Stanley, Shen, Defen, Chu, Xi Kathy, Yu, Cheng-Rong, Abu-Asab, Mones, Tuo, Jingsheng, Eberhart, Charles G., Olsen, Timothy W., Mullins, Robert F., White, Gary, Wadsworth, Sam, Scaria, Abraham, Chan, Chi-Chao
Izdano 2014

Soluble FLT1 Gene Therapy Alleviates Brain Arteriovenous Malformation Severity

od Zhu, Wan, Shen, Fanxia, Mao, Lei, Zhan, Lei, Kang, Shuai, Sun, Zhengda, Nelson, Jeffrey, Zhang, Rui, Zou, Dingquan, McDougall, Cameron M., Lawton, Michael T., Vu, Thiennu H., Wu, Zhijian, Scaria, Abraham, Colosi, Peter, Forsayeth, John, Su, Hua
Izdano u Stroke (2017)

Improved CRISPR genome editing using small highly active and specific engineered RNA-guided nucleases

od Schmidt, Moritz J., Gupta, Ashish, Bednarski, Christien, Gehrig-Giannini, Stefanie, Richter, Florian, Pitzler, Christian, Gamalinda, Michael, Galonska, Christina, Takeuchi, Ryo, Wang, Kui, Reiss, Caroline, Dehne, Kerstin, Lukason, Michael J., Noma, Akiko, Park-Windhol, Cindy, Allocca, Mariacarmela, Kantardzhieva, Albena, Sane, Shailendra, Kosakowska, Karolina, Cafferty, Brian, Tebbe, Jan, Spencer, Sarah J., Munzer, Scott, Cheng, Christopher J., Scaria, Abraham, Scharenberg, Andrew M., Cohnen, André, Coco, Wayne M.
Izdano u Nat Commun (2021)