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AAV5-mediated sFLT01 gene therapy arrests retinal lesions in Ccl2(−/−) /Cx3cr1(−)(/)(−) mice
To test the effects of adeno-associated virus encoding sFLT01 (AAV5.sFLT01) on the retinal lesions in Ccl2(−/−)/Cx3cr1(−/−) mice, a model for age-related macular degeneration (AMD), AAV5.sFLT01 was injected into the subretinal space of the right eyes and the left eye was served as controls. Histolog...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3136657/ https://ncbi.nlm.nih.gov/pubmed/21397984 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2011.01.009 |
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