Naloxone Ameliorates Retinal Lesions in Ccl2/Cx3cr1 Double-Deficient Mice via Modulation of Microglia

PURPOSE. The role of naloxone, an opioid receptor antagonist, on microglial inhibition and neuroprotective effects has been reported in lipopolysaccharide (LPS)-induced neurodegeneration and light-induced photoreceptor degeneration. The authors evaluated the effects of naloxone on Ccl2(−/−)/Cx3cr1(−...

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Main Authors: Shen, Defen, Cao, Xiaoguang, Zhao, Lian, Tuo, Jingsheng, Wong, Wai T., Chan, Chi-Chao
Format: Artigo
Sprog:Inglês
Udgivet: Association for Research in Vision and Ophthalmology, Inc. 2011
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3109007/
https://ncbi.nlm.nih.gov/pubmed/21245403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-6114
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