AAV5-mediated sFLT01 gene therapy arrests retinal lesions in Ccl2(−/−) /Cx3cr1(−)(/)(−) mice

To test the effects of adeno-associated virus encoding sFLT01 (AAV5.sFLT01) on the retinal lesions in Ccl2(−/−)/Cx3cr1(−/−) mice, a model for age-related macular degeneration (AMD), AAV5.sFLT01 was injected into the subretinal space of the right eyes and the left eye was served as controls. Histolog...

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Hlavní autoři: Tuo, Jingsheng, Pang, Ji-Jing, Cao, Xiaoguang, Shen, Defen, Zhang, Jun, Scaria, Abraham, Wadsworth, Samuel C., Pechan, Peter, Boye, Sanford L., Hauswirth, William W., Chan, Chi-Chao
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136657/
https://ncbi.nlm.nih.gov/pubmed/21397984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2011.01.009
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