Soluble FLT1 Gene Therapy Alleviates Brain Arteriovenous Malformation Severity

BACKGROUND AND PURPOSE: Brain arteriovenous malformation (bAVM) is an important risk factor for intracranial hemorrhage. Current therapies are associated with high morbidities. Excessive vascular endothelial growth factor (VEGF) has been implicated in bAVM pathophysiology. Because soluble FLT1 binds...

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Detalhes bibliográficos
Publicado no:Stroke
Main Authors: Zhu, Wan, Shen, Fanxia, Mao, Lei, Zhan, Lei, Kang, Shuai, Sun, Zhengda, Nelson, Jeffrey, Zhang, Rui, Zou, Dingquan, McDougall, Cameron M., Lawton, Michael T., Vu, Thiennu H., Wu, Zhijian, Scaria, Abraham, Colosi, Peter, Forsayeth, John, Su, Hua
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404983/
https://ncbi.nlm.nih.gov/pubmed/28325846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.116.015713
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