Soluble FLT1 Gene Therapy Alleviates Brain Arteriovenous Malformation Severity

BACKGROUND AND PURPOSE: Brain arteriovenous malformation (bAVM) is an important risk factor for intracranial hemorrhage. Current therapies are associated with high morbidities. Excessive vascular endothelial growth factor (VEGF) has been implicated in bAVM pathophysiology. Because soluble FLT1 binds...

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發表在:Stroke
Main Authors: Zhu, Wan, Shen, Fanxia, Mao, Lei, Zhan, Lei, Kang, Shuai, Sun, Zhengda, Nelson, Jeffrey, Zhang, Rui, Zou, Dingquan, McDougall, Cameron M., Lawton, Michael T., Vu, Thiennu H., Wu, Zhijian, Scaria, Abraham, Colosi, Peter, Forsayeth, John, Su, Hua
格式: Artigo
語言:Inglês
出版: 2017
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404983/
https://ncbi.nlm.nih.gov/pubmed/28325846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.116.015713
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