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Inhibition of pathological brain angiogenesis through systemic delivery of AAV vector expressing soluble FLT1
The soluble vascular endothelial growth factor (VEGF) receptor 1 (sFLT1) has been tested in both animals and humans for anti-angiogenic therapies, e.g., age-related macular degeneration. We hypothesized that adeno-associated viral vector (AAV)-mediated sFLT1 expression could be used to inhibit abnor...
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| Pubblicato in: | Gene Ther |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4636448/ https://ncbi.nlm.nih.gov/pubmed/26090874 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2015.57 |
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