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Effect of Genome Size on AAV Vector Packaging

Adeno-associated virus (AAV) vector genomes have been limited to 5 kilobases (kb) in length because their packaging limit was thought to be similar to the size of the parent AAV genome. Recent reports claim that significantly larger vector genomes can be packaged intact. We examined the packaged vec...

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Detalhes bibliográficos
Main Authors: Wu, Zhijian, Yang, Hongyan, Colosi, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2839202/
https://ncbi.nlm.nih.gov/pubmed/19904234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.255
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