Interleukin 35–Producing B Cells (i35-Breg): A New Mediator of Regulatory B-Cell Functions in CNS Autoimmune Diseases

Por Egwuagu, Charles E., Yu, Cheng-Rong
Publicado no Crit Rev Immunol (2015)

Interleukin 35: Critical Regulator of Immunity and Lymphocyte-mediated Diseases

Por Egwuagu, Charles E., Yu, Cheng-Rong, Sun, Lin, Wang, Renxi
Publicado no Cytokine Growth Factor Rev (2015)

Loss of STAT3 in CD4(+) T cells prevents development of experimental autoimmune diseases

Por Liu, Xuebin, Lee, Yun sang, Yu, Cheng-Rong, Egwuagu, Charles E.
Publicado em 2008

STAT3 Activates miR-155 in Th17 Cells and Acts in Concert to Promote Experimental Autoimmune Uveitis

Por Escobar, Thelma, Yu, Cheng-Rong, Muljo, Stefan A., Egwuagu, Charles E.
Publicado em 2013

Retinal cells suppress intraocular inflammation (uveitis) through production of interleukin-27 and interleukin-10

Por Lee, Yun Sang, Amadi-Obi, Ahjoku, Yu, Cheng-Rong, Egwuagu, Charles E
Publicado em 2011

Novel IL27p28/IL12p40 Cytokine Suppressed Experimental Autoimmune Uveitis by Inhibiting Autoreactive Th1/Th17 Cells and Promoting Expansion of Regulatory T Cells

Por Wang, Ren-Xi, Yu, Cheng-Rong, Mahdi, Rashid M., Egwuagu, Charles E.
Publicado em 2012

SOCS3 Deletion in T-Lymphocytes Suppresses Development of Chronic Ocular Inflammation Via Up-regulation of CTLA-4 and Expansion of Regulatory T cells

Por Yu, Cheng-Rong, Kim, Sung-Hye, Mahdi, Rashid M., Egwuagu, Charles E.
Publicado em 2013

STAT3 Protein Interacts with Class O Forkhead Transcription Factors in the Cytoplasm and Regulates Nuclear/Cytoplasmic Localization of FoxO1 and FoxO3a Proteins in CD4(+) T Cells

Por Oh, Hyun-Mee, Yu, Cheng-Rong, Dambuza, Ivy, Marrero, Bernadette, Egwuagu, Charles E.
Publicado em 2012

Therapeutic Targeting of STAT3 (Signal Transducers and Activators of Transcription 3) Pathway Inhibits Experimental Autoimmune Uveitis

Por Yu, Cheng-Rong, Lee, Yun Sang, Mahdi, Rashid M., Surendran, Narayanan, Egwuagu, Charles E.
Publicado em 2012

Deletion of Irf4 in T Cells Suppressed Autoimmune Uveitis and Dysregulated Transcriptional Programs Linked to CD4(+) T Cell Differentiation and Metabolism

Por Kang, Minkyung, Lee, Hyun-Su, Choi, Jin Kyeong, Yu, Cheng-Rong, Egwuagu, Charles E.
Publicado no Int J Mol Sci (2021)

STAT3 Regulates Proliferation and Survival of CD8(+) T Cells: Enhances Effector Responses to HSV-1 Infection, and Inhibits IL-10(+) Regulatory CD8(+) T Cells in Autoimmune Uveitis

Por Yu, Cheng-Rong, Dambuza, Ivy M., Lee, Yong-Jun, Frank, Gregory M., Egwuagu, Charles E.
Publicado em 2013

Topical administration of a Suppressor of Cytokine Signaling-1 (SOCS1) mimetic peptide inhibits ocular inflammation and mitigates ocular pathology during mouse uveitis

Por He, Chang, Yu, Cheng-Rong, Sun, Lin, Mahdi, Rashid M, Larkin, Joseph, Egwuagu, Charles E.
Publicado no J Autoimmun (2015)

Interleukin 27 Induces the Expression of Complement Factor H (CFH) in the Retina

Por Amadi-Obi, Ahjoku, Yu, Cheng-Rong, Dambuza, Ivy, Kim, Sung-Hye, Marrero, Bernadette, Egwuagu, Charles E.
Publicado em 2012

SOCS1 Mimetic Peptide Suppresses Chronic Intraocular Inflammatory Disease (Uveitis)

Por He, Chang, Yu, Cheng-Rong, Mattapallil, Mary J., Sun, Lin, Larkin III, Joseph, Egwuagu, Charles E.
Publicado no Mediators Inflamm (2016)

STAT3 deficiency in B cells exacerbates uveitis by promoting expansion of pathogenic lymphocytes and suppressing regulatory B cells (Bregs) and Tregs

Por Oladipupo, Favour O., Yu, Cheng-Rong, Olumuyide, Ezekiel, Jittaysothorn, Yingyos, Choi, Jin Kyeong, Egwuagu, Charles E.
Publicado no Sci Rep (2020)

SOCS1 Regulates CCR7 expression and Migration of CD4(+) T Cells into peripheral Tissues

Por Yu, Cheng-Rong, Mahdi, Rashid M., Liu, Xuebin, Zhang, Allen, Naka, Tetsuji, Kishimoto, Tadamitsu, Egwuagu, Charles E.
Publicado em 2008

Autoreactive Memory CD4(+) T Lymphocytes that mediate Chronic Uveitis Reside in the Bone Marrow through STAT3-dependent Mechanisms

Por Oh, Hyun-Mee, Yu, Cheng-Rong, Lee, YongJun, Chan, Chi-Chao, Maminishkis, Arvydas, Egwuagu, Charles E.
Publicado em 2011

Enhanced apoptosis in retinal pigment epithelium under inflammatory stimuli and oxidative stress

Por Wang, Yujuan, Shen, Defen, Wang, Vinson M., Yu, Cheng-Rong, Wang, Ren-Xi, Tuo, Jingsheng, Chan, Chi-Chao
Publicado em 2012

Key role for IL-21 in experimental autoimmune uveitis

Por Wang, Lu, Yu, Cheng-Rong, Kim, Hyoung-Pyo, Liao, Wei, Telford, William G., Egwuagu, Charles E., Leonard, Warren J.
Publicado em 2011

Platelet-derived growth factor (PDGF)-C inhibits neuroretinal apoptosis in a murine model of focal retinal degeneration

Por Wang, Yujuan, Abu-Asab, Mones S., Yu, Cheng-Rong, Tang, Zhongshu, Shen, Defen, Tuo, Jingsheng, Li, Xuri, Chan, Chi-Chao
Publicado em 2014