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Topical administration of a Suppressor of Cytokine Signaling-1 (SOCS1) mimetic peptide inhibits ocular inflammation and mitigates ocular pathology during mouse uveitis

Uveitis is a diverse group of potentially sight-threatening intraocular inflammatory diseases and pathology derives from sustained production of pro-inflammatory cytokines in the optical axis. Although topical or systemic steroids are effective therapies, their adverse effects preclude prolonged usa...

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Détails bibliographiques
Publié dans:J Autoimmun
Auteurs principaux: He, Chang, Yu, Cheng-Rong, Sun, Lin, Mahdi, Rashid M, Larkin, Joseph, Egwuagu, Charles E.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4529792/
https://ncbi.nlm.nih.gov/pubmed/26094775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2015.05.011
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