Inhibition of Choroidal Neovascularization in a Nonhuman Primate Model by Intravitreal Administration of an AAV2 Vector Expressing a Novel Anti-VEGF Molecule

Inhibition of vascular endothelial growth factor (VEGF) for the management of the pathological ocular neovascularization associated with diseases such as neovascular age-related macular degeneration is a proven paradigm; however, monthly intravitreal injections are required for optimal treatment. We...

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Main Authors: Lukason, Michael, DuFresne, Elizabeth, Rubin, Hillard, Pechan, Peter, Li, Qiuhong, Kim, Ivana, Kiss, Szilard, Flaxel, Christina, Collins, Margaret, Miller, Joan, Hauswirth, William, MacLachlan, Timothy, Wadsworth, Samuel, Scaria, Abraham
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2011
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3034843/
https://ncbi.nlm.nih.gov/pubmed/20978476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.230
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