Hedgehog-gli signaling in human disease

Por Ruiz i Altaba, Ariel.
Publicado em 2006

A GLI1-p53 inhibitory loop controls neural stem cell and tumour cell numbers

Por Stecca, Barbara, Ruiz i Altaba, Ariel
Publicado em 2009

Context-dependent Regulation of the GLI Code in Cancer by HEDGEHOG and Non-HEDGEHOG Signals

Por Stecca, Barbara, Ruiz i Altaba, Ariel
Publicado em 2010

Context-dependent signal integration by the GLI code: The oncogenic load, pathways, modifiers and implications for cancer therapy

Por Aberger, Fritz, Ruiz i Altaba, Ariel
Publicado em 2014

Metastases and Colon Cancer Tumor Growth Display Divergent Responses to Modulation of Canonical WNT Signaling

Por Seth, Chandan, Ruiz i Altaba, Ariel
Publicado no PLoS One (2016)

Correction: Metastases and Colon Cancer Tumor Growth Display Divergent Responses to Modulation of Canonical WNT Signaling

Por Seth, Chandan, Ruiz i Altaba, Ariel
Publicado no PLoS One (2016)

The Gli code: an information nexus regulating cell fate, stemness and cancer

Por Ruiz i Altaba, Ariel, Mas, Christophe, Stecca, Barbara
Publicado em 2007

Loss of WNT-TCF addiction and enhancement of HH-GLI1 signalling define the metastatic transition of human colon carcinomas

Por Varnat, Frédéric, Siegl-Cachedenier, Irene, Malerba, Monica, Gervaz, Pascal, Ruiz i Altaba, Ariel
Publicado em 2010

The river blindness drug Ivermectin and related macrocyclic lactones inhibit WNT-TCF pathway responses in human cancer

Por Melotti, Alice, Mas, Christophe, Kuciak, Monika, Lorente-Trigos, Aiala, Borges, Isabel, Ruiz i Altaba, Ariel
Publicado no EMBO Mol Med (2014)

In vivo epigenetic reprogramming of primary human colon cancer cells enhances metastases

Por Singovski, Grigori, Bernal, Carolina, Kuciak, Monika, Siegl-Cachedenier, Irene, Conod, Arwen, Ruiz i Altaba, Ariel
Publicado no J Mol Cell Biol (2016)

NANOG regulates glioma stem cells and is essential in vivo acting in a cross-functional network with GLI1 and p53

Por Zbinden, Marie, Duquet, Arnaud, Lorente-Trigos, Aiala, Ngwabyt, Sandra-Nadia, Borges, Isabel, Ruiz i Altaba, Ariel
Publicado em 2010

Human colon cancer epithelial cells harbour active HEDGEHOG-GLI signalling that is essential for tumour growth, recurrence, metastasis and stem cell survival and expansion

Por Varnat, Frédéric, Duquet, Arnaud, Malerba, Monica, Zbinden, Marie, Mas, Christophe, Gervaz, Pascal, Ruiz i Altaba, Ariel
Publicado em 2009

A novel genome-wide in vivo screen for metastatic suppressors in human colon cancer identifies the positive WNT-TCF pathway modulators TMED3 and SOX12

Por Duquet, Arnaud, Melotti, Alice, Mishra, Sonakshi, Malerba, Monica, Seth, Chandan, Conod, Arwen, Ruiz i Altaba, Ariel
Publicado em 2014

Melanomas require HEDGEHOG-GLI signaling regulated by interactions between GLI1 and the RAS-MEK/AKT pathways

Por Stecca, Barbara, Mas, Christophe, Clement, Virginie, Zbinden, Marie, Correa, Rafael, Piguet, Vincent, Beermann, Friedrich, Ruiz i Altaba, Ariel
Publicado em 2007

Long-Lasting WNT-TCF Response Blocking and Epigenetic Modifying Activities of Withanolide F in Human Cancer Cells

Por Seth, Chandan, Mas, Christophe, Conod, Arwen, Mueller, Jens, Siems, Karsten, Kuciak, Monika, Borges, Isabel, Ruiz i Altaba, Ariel
Publicado no PLoS One (2016)

Inhibition of prostate cancer proliferation by interference with SONIC HEDGEHOG-GLI1 signaling

Por Sanchez, Pilar, Hernández, Ana Maria, Stecca, Barbara, Kahler, Andrea J., DeGueme, Amy M., Barrett, Andrea, Beyna, Mercedes, Datta, Milton W., Datta, Sumana, Ruiz i Altaba, Ariel
Publicado em 2004