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In vivo epigenetic reprogramming of primary human colon cancer cells enhances metastases
How metastases develop is not well understood and no genetic mutations have been reported as specific metastatic drivers. Here we have addressed the idea that epigenetic reprogramming by GLI-regulated pluripotent stemness factors promotes metastases. Using primary human colon cancer cells engrafted...
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| Publicado no: | J Mol Cell Biol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4816146/ https://ncbi.nlm.nih.gov/pubmed/26031752 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jmcb/mjv034 |
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