Inhibition of prostate cancer proliferation by interference with SONIC HEDGEHOG-GLI1 signaling

Prostate cancer is the most common solid tumor in men, and it shares with all cancers the hallmark of elevated, nonhomeostatic cell proliferation. Here we have tested the hypothesis that the SONIC HEDGEHOG (SHH)–GLI signaling pathway is implicated in prostate cancer. We report expression of SHH–GLI...

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Detalhes bibliográficos
Main Authors: Sanchez, Pilar, Hernández, Ana Maria, Stecca, Barbara, Kahler, Andrea J., DeGueme, Amy M., Barrett, Andrea, Beyna, Mercedes, Datta, Milton W., Datta, Sumana, Ruiz i Altaba, Ariel
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC514658/
https://ncbi.nlm.nih.gov/pubmed/15314219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0404956101
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