Inhibition of prostate cancer proliferation by interference with SONIC HEDGEHOG-GLI1 signaling

Prostate cancer is the most common solid tumor in men, and it shares with all cancers the hallmark of elevated, nonhomeostatic cell proliferation. Here we have tested the hypothesis that the SONIC HEDGEHOG (SHH)–GLI signaling pathway is implicated in prostate cancer. We report expression of SHH–GLI...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Sanchez, Pilar, Hernández, Ana Maria, Stecca, Barbara, Kahler, Andrea J., DeGueme, Amy M., Barrett, Andrea, Beyna, Mercedes, Datta, Milton W., Datta, Sumana, Ruiz i Altaba, Ariel
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2004
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC514658/
https://ncbi.nlm.nih.gov/pubmed/15314219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0404956101
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