Inhibition of prostate cancer proliferation by interference with SONIC HEDGEHOG-GLI1 signaling

Prostate cancer is the most common solid tumor in men, and it shares with all cancers the hallmark of elevated, nonhomeostatic cell proliferation. Here we have tested the hypothesis that the SONIC HEDGEHOG (SHH)–GLI signaling pathway is implicated in prostate cancer. We report expression of SHH–GLI...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Sanchez, Pilar, Hernández, Ana Maria, Stecca, Barbara, Kahler, Andrea J., DeGueme, Amy M., Barrett, Andrea, Beyna, Mercedes, Datta, Milton W., Datta, Sumana, Ruiz i Altaba, Ariel
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2004
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC514658/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15314219/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0404956101
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