Inhibition of prostate cancer proliferation by interference with SONIC HEDGEHOG-GLI1 signaling

Prostate cancer is the most common solid tumor in men, and it shares with all cancers the hallmark of elevated, nonhomeostatic cell proliferation. Here we have tested the hypothesis that the SONIC HEDGEHOG (SHH)–GLI signaling pathway is implicated in prostate cancer. We report expression of SHH–GLI...

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Autors principals: Sanchez, Pilar, Hernández, Ana Maria, Stecca, Barbara, Kahler, Andrea J., DeGueme, Amy M., Barrett, Andrea, Beyna, Mercedes, Datta, Milton W., Datta, Sumana, Ruiz i Altaba, Ariel
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2004
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC514658/
https://ncbi.nlm.nih.gov/pubmed/15314219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0404956101
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