Perlecan, a candidate gene for the CAPB locus, regulates prostate cancer cell growth via the Sonic Hedgehog pathway

BACKGROUND: Genetic studies associated the CAPB locus with familial risk of brain and prostate cancers. We have identified HSPG2 (Perlecan) as a candidate gene for CAPB. Previously we have linked Perlecan to Hedgehog signaling in Drosophila. More recently, we have demonstrated the importance of Hedg...

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Detalhes bibliográficos
Principais autores: Datta, Milton W, Hernandez, Ana Maria, Schlicht, Michael J, Kahler, Andrea J, DeGueme, Amy M, Dhir, Rajiv, Shah, Rajal B, Farach-Carson, Cindy, Barrett, Andrea, Datta, Sumana
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1421430/
https://ncbi.nlm.nih.gov/pubmed/16507112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-5-9
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