The Structural Basis and Functional Consequences of Interactions Between Tetrodotoxin and Voltage-Gated Sodium Channels

par Geffeney, Shana L., Ruben, Peter C.
Publié 2006

Protein Kinases Mediate Anti-Inflammatory Effects of Cannabidiol and Estradiol Against High Glucose in Cardiac Sodium Channels

par Fouda, Mohamed A., Ruben, Peter C.
Publié dans Front Pharmacol (2021)

A thermosensitive mutation alters the effects of lacosamide on slow inactivation in neuronal voltage-gated sodium channels, Na(V)1.2

par Abdelsayed, Mena, Sokolov, Stanislav, Ruben, Peter C.
Publié 2013

The efficacy of Ranolazine on E1784K is altered by temperature and calcium

par Abdelsayed, Mena, Ruprai, Manpreet, Ruben, Peter C.
Publié dans Sci Rep (2018)

A defect in skeletal muscle sodium channel deactivation exacerbates hyperexcitability in human paramyotonia congenita

par Featherstone, David E, Fujimoto, Esther, Ruben, Peter C
Publié 1998

Negative charges in the DIII–DIV linker of human skeletal muscle Na(+) channels regulate deactivation gating

par Groome, James R, Fujimoto, Esther, Ruben, Peter C
Publié 2003

Differential thermosensitivity in mixed syndrome cardiac sodium channel mutants

par Abdelsayed, Mena, Peters, Colin H, Ruben, Peter C
Publié dans J Physiol (2015)

Effects of Amiodarone and N-desethylamiodarone on Cardiac Voltage-Gated Sodium Channels

par Ghovanloo, Mohammad-Reza, Abdelsayed, Mena, Ruben, Peter C.
Publié dans Front Pharmacol (2016)

Arrhythmogenic triggers associated with Sudden Cardiac Death

par Abdelsayed, Mena, Peters, Colin H., Ruben, Peter C.
Publié dans Channels (Austin) (2017)

Acidosis Differentially Modulates Inactivation in Na(V)1.2, Na(V)1.4, and Na(V)1.5 Channels

par Vilin, Yury Y., Peters, Colin H., Ruben, Peter C.
Publié 2012

Effects of acidosis on neuronal voltage-gated sodium channels: Nav1.1 and Nav1.3

par Ghovanloo, Mohammad-Reza, Peters, Colin H., Ruben, Peter C.
Publié dans Channels (Austin) (2018)

Cannabidiol protects against high glucose‐induced oxidative stress and cytotoxicity in cardiac voltage‐gated sodium channels

par Fouda, Mohamed A., Ghovanloo, Mohammad‐Reza, Ruben, Peter C.
Publié dans Br J Pharmacol (2020)

5HT1A Serotonin Receptor Agonists Inhibit Plasmodium falciparum by Blocking a Membrane Channel

par Locher, Christopher P., Ruben, Peter C., Gut, Jiri, Rosenthal, Philip J.
Publié 2003

Charge Immobilization of Skeletal Muscle Na(+) Channels: Role of Residues in the Inactivation Linker

par Groome, James R., Dice, Margaret C., Fujimoto, Esther, Ruben, Peter C.
Publié 2007

Differential effects of homologous S4 mutations in human skeletal muscle sodium channels on deactivation gating from open and inactivated states

par Groome, James R, Fujimoto, Esther, George, Alfred L, Ruben, Peter C
Publié 1999

A Mixed Periodic Paralysis & Myotonia Mutant, P1158S, Imparts pH-Sensitivity in Skeletal Muscle Voltage-gated Sodium Channels

par Ghovanloo, Mohammad-Reza, Abdelsayed, Mena, Peters, Colin H., Ruben, Peter C.
Publié dans Sci Rep (2018)

Biophysical Characterization of a Novel SCN5A Mutation Associated With an Atypical Phenotype of Atrial and Ventricular Arrhythmias and Sudden Death

par Ghovanloo, Mohammad-Reza, Atallah, Joseph, Escudero, Carolina A., Ruben, Peter C.
Publié dans Front Physiol (2020)

E1784K, the most common Brugada syndrome and long-QT syndrome type 3 mutant, disrupts sodium channel inactivation through two separate mechanisms

par Peters, Colin H., Watkins, Abeline R., Poirier, Olivia L., Ruben, Peter C.
Publié dans J Gen Physiol (2020)

Depolarization of the conductance-voltage relationship in the Na(V)1.5 mutant, E1784K, is due to altered fast inactivation

par Peters, Colin H., Yu, Alec, Zhu, Wandi, Silva, Jonathan R., Ruben, Peter C.
Publié dans PLoS One (2017)

Proton Sensors in the Pore Domain of the Cardiac Voltage-gated Sodium Channel

par Jones, David K., Peters, Colin H., Allard, Charlene R., Claydon, Tom W., Ruben, Peter C.
Publié 2013