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Differential thermosensitivity in mixed syndrome cardiac sodium channel mutants
Cardiac arrhythmias are often associated with mutations in SCN5A the gene that encodes the cardiac paralogue of the voltage-gated sodium channel, Na(V)1.5. The Na(V)1.5 mutants R1193Q and E1784K give rise to both long QT and Brugada syndromes. Various environmental factors, including temperature, ma...
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| Publicado no: | J Physiol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley & Sons, Ltd
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4594293/ https://ncbi.nlm.nih.gov/pubmed/26131924 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP270139 |
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