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Cannabidiol protects against high glucose‐induced oxidative stress and cytotoxicity in cardiac voltage‐gated sodium channels

BACKGROUND AND PURPOSE: Cardiovascular complications are the major cause of mortality in diabetic patients. However, the molecular mechanisms underlying diabetes‐associated arrhythmias are unclear. We hypothesized that high glucose could adversely affect Na(v)1.5, the major cardiac sodium channel is...

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Библиографические подробности
Опубликовано в: :Br J Pharmacol
Главные авторы: Fouda, Mohamed A., Ghovanloo, Mohammad‐Reza, Ruben, Peter C.
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7279989/
https://ncbi.nlm.nih.gov/pubmed/32077098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.15020
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