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Proton Sensors in the Pore Domain of the Cardiac Voltage-gated Sodium Channel
Protons impart isoform-specific modulation of inactivation in neuronal, skeletal muscle, and cardiac voltage-gated sodium (Na(V)) channels. Although the structural basis of proton block in Na(V) channels has been well described, the amino acid residues responsible for the changes in Na(V) kinetics d...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3576083/ https://ncbi.nlm.nih.gov/pubmed/23283979 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.434266 |
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