Loading...

Charge Immobilization of Skeletal Muscle Na(+) Channels: Role of Residues in the Inactivation Linker

We investigated structural determinants of fast inactivation and deactivation in sodium channels by comparing ionic flux and charge movement in skeletal muscle channels, using mutations of DIII-DIV linker charges. Charge altering and substituting mutations at K-1317, K-1318 depolarized the g(V) curv...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Groome, James R., Dice, Margaret C., Fujimoto, Esther, Ruben, Peter C.
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1948039/
https://ncbi.nlm.nih.gov/pubmed/17513361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.102079
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!