Synthetic Immunology: Hacking Immune Cells to Expand Their Therapeutic Capabilities

ανά Roybal, Kole T., Lim, Wendell A.
Τόπος έκδοσης Annu Rev Immunol (2017)

Tentative and transient natural killer cell polarization balances the requirements for discriminatory recognition and cytolytic efficacy

ανά Sinai, Parisa, Roybal, Kole T, Wülfing, Christoph
Έκδοση 2010

Synthetic Biology Approaches to Engineer T cells

ανά Wu, Chia-Yung, Rupp, Levi J., Roybal, Kole T., Lim, Wendell A.
Τόπος έκδοσης Curr Opin Immunol (2015)

Differential Regulation of the Period Genes in Striatal Regions following Cocaine Exposure

ανά Falcon, Edgardo, Ozburn, Angela, Mukherjee, Shibani, Roybal, Kole, McClung, Colleen A.
Έκδοση 2013

Remote control of therapeutic T cells through a small molecule-gated chimeric receptor

ανά Wu, Chia-Yung, Roybal, Kole T., Puchner, Elias M., Onuffer, James, Lim, Wendell A.
Τόπος έκδοσης Science (2015)

Early Signaling in Primary T Cells Activated by Antigen Presenting Cells Is Associated with a Deep and Transient Lamellal Actin Network

ανά Roybal, Kole T., Mace, Emily M., Mantell, Judith M., Verkade, Paul, Orange, Jordan S., Wülfing, Christoph
Τόπος έκδοσης PLoS One (2015)

IFN-α suppresses GATA3 transcription from a distal exon and promotes H3K27 tri-methylation of the CNS-1 enhancer in human Th2 cells()

ανά Huber, Jonathan P., Gonzales-van Horn, Sarah R., Roybal, Kole T., Gill, Michelle A., Farrar, J. David
Έκδοση 2014

IMMU-57. SEQUENTIAL TWO-RECEPTOR PRIMING CAR SYSTEM TO OVERCOME HETEROGENEOUS ANTIGEN EXPRESSION

ανά Watchmaker, Payal, Choe, Joseph, Carrera, Diego, Downey, Kira, Shahin, Maryam, Roybal, Kole, Lim, Wendell, Okada, Hideho
Τόπος έκδοσης Neuro Oncol (2018)

Engineering Customized Cell Sensing and Response Behaviors Using Synthetic Notch Receptors

ανά Morsut, Leonardo, Roybal, Kole T., Xiong, Xin, Gordley, Russell M., Coyle, Scott M., Thomson, Matthew, Lim, Wendell A.
Τόπος έκδοσης Cell (2016)

CRISPR/Cas9-mediated PD-1 disruption enhances anti-tumor efficacy of human chimeric antigen receptor T cells

ανά Rupp, Levi J., Schumann, Kathrin, Roybal, Kole T., Gate, Rachel E., Ye, Chun J., Lim, Wendell A., Marson, Alexander
Τόπος έκδοσης Sci Rep (2017)

IMMU-21. SEQUENTIAL TWO-RECEPTOR PRIMING CAR SYSTEM TO OVERCOME HETEROGENEOUS ANTIGEN EXPRESSION

ανά Watchmaker, Payal, Choe, Joseph, Carrera, Diego, Gilbert, Ryan, Yu, Wei, Downey, Kira, Roybal, Kole, Lim, Wendell, Okada, Hideho
Τόπος έκδοσης Neuro Oncol (2019)

Spatiotemporal Patterning During T Cell Activation Is Highly Diverse

ανά Singleton, Kentner L., Roybal, Kole T., Sun, Yi, Fu, Guo, Gascoigne, Nicholas R. J., van Oers, Nicolai S. C., Wülfing, Christoph
Έκδοση 2009

Modest Interference with Actin Dynamics in Primary T Cell Activation by Antigen Presenting Cells Preferentially Affects Lamellal Signaling

ανά Roybal, Kole T., Mace, Emily M., Clark, Danielle J., Leard, Alan D., Herman, Andrew, Verkade, Paul, Orange, Jordan S., Wülfing, Christoph
Τόπος έκδοσης PLoS One (2015)

Precision Tumor Recognition by T Cells With Combinatorial Antigen Sensing Circuits

ανά Roybal, Kole T., Rupp, Levi J., Morsut, Leonardo, Walker, Whitney J., McNally, Krista A., Park, Jason S., Lim, Wendell A.
Τόπος έκδοσης Cell (2016)

convertibleCARs: A chimeric antigen receptor system for flexible control of activity and antigen targeting

ανά Landgraf, Kyle E., Williams, Steven R., Steiger, Daniel, Gebhart, Dana, Lok, Stephen, Martin, David W., Roybal, Kole T., Kim, Kaman Chan
Τόπος έκδοσης Commun Biol (2020)

Enhancement of anti-tumor CD8 immunity by IgG1-mediated targeting of Fc receptors

ανά Furlan, Scott N, Mandraju, Rajakumar, Brewer, Travis, Roybal, Kole, Troutman, Ty Dale, Hu, Wei, Palm, Noah W, Unni, Arun, Pasare, Chandrashekhar
Έκδοση 2014

Mycobacterial Shuttle Vectors Designed for High-Level Protein Expression in Infected Macrophages

ανά Eitson, Jennifer L., Medeiros, Jennifer J., Hoover, Ashley R., Srivastava, Shashikant, Roybal, Kole T., Aínsa, José A., Hansen, Eric J., Gumbo, Tawanda, van Oers, Nicolai S. C.
Έκδοση 2012

Engineering T cells with Customized Therapeutic Response Programs Using Synthetic Notch Receptors

ανά Roybal, Kole T., Williams, Jasper Z., Morsut, Leonardo, Rupp, Levi J., Kolinko, Isabel, Choe, Joseph H., Walker, Whitney J., McNally, Krista A., Lim, Wendell A.
Τόπος έκδοσης Cell (2016)

Computational spatiotemporal analysis identifies WAVE2 and Cofilin as joint regulators of costimulation-mediated T cell actin dynamics

ανά Roybal, Kole T., Buck, Taráz E., Ruan, Xiongtao, Cho, Baek Hwan, Clark, Danielle J., Ambler, Rachel, Tunbridge, Helen M., Zhang, Jianwei, Verkade, Paul, Wülfing, Christoph, Murphy, Robert F.
Τόπος έκδοσης Sci Signal (2016)

The CD3 ζ subunit contains a phosphoinositide-binding motif that is required for the stable accumulation of TCR/CD3 complex at the immunological synapse

ανά DeFord-Watts, Laura M., Dougall, David S., Belkaya, Serkan, Johnson, Blake A., Eitson, Jennifer L., Roybal, Kole T., Barylko, Barbara, Albanesi, Joseph P., Wülfing, Christoph, van Oers, Nicolai S.C.
Έκδοση 2011