Molecular Mechanism of an Oncogenic Mutation That Alters Membrane Targeting: Glu17Lys Modifies the PIP Lipid Specificity of the AKT1 PH Domain

Por Landgraf, Kyle E., Pilling, Carissa, Falke, Joseph J.
Publicado em 2008

GRP1 PH Domain, Like AKT1 PH Domain, Possesses a Sentry Glutamate Residue Essential for Specific Targeting to Plasma Membrane PI(3,4,5)P(3)

Por Pilling, Carissa, Landgraf, Kyle E., Falke, Joseph J.
Publicado em 2011

Effect of PIP(2) Binding on the Membrane Docking Geometry of PKCα C2 Domain: An EPR Site-Directed Spin-Labeling and Relaxation Study()

Por Landgraf, Kyle E., Malmberg, Nathan J., Falke, Joseph J.
Publicado em 2008

Mechanism of Specific Membrane Targeting by C2 Domains: Localized Pools of Target Lipids Enhance Ca(2+) Affinity

Por Corbin, John A., Evans, John H., Landgraf, Kyle E., Falke, Joseph J.
Publicado em 2007

Membrane Docking Geometry and Target Lipid Stoichiometry of Membrane-Bound PKCα C2 Domain: A Combined Molecular Dynamics and Experimental Study

Por Lai, Chun-Liang, Landgraf, Kyle E., Voth, Gregory A., Falke, Joseph J.
Publicado em 2010

Membrane Docking Geometry of GRP1 PH Domain Bound to a Target Lipid Bilayer: An EPR Site-Directed Spin-Labeling and Relaxation Study

Por Chen, Huai-Chun, Ziemba, Brian P., Landgraf, Kyle E., Corbin, John A., Falke, Joseph J.
Publicado em 2012

Single-Molecule Studies Reveal a Hidden Key Step in the Activation Mechanism of Membrane-Bound Protein Kinase C-α

Por Ziemba, Brian P., Li, Jianing, Landgraf, Kyle E., Knight, Jefferson D., Voth, Gregory A., Falke, Joseph J.
Publicado em 2014

Allosteric Peptide Activators of Pro-Hepatocyte Growth Factor Stimulate Met Signaling

Por Landgraf, Kyle E., Santell, Lydia, Billeci, Karen L., Quan, Clifford, Young, Judy C., Maun, Henry R., Kirchhofer, Daniel, Lazarus, Robert A.
Publicado em 2010

Evidence that opioids may have toll like receptor 4 and MD-2 effects

Por Hutchinson, Mark R., Zhang, Yingning, Shridhar, Mitesh, Evans, John H., Buchanan, Madison M., Zhao, Tina X., Slivka, Peter F., Coats, Benjamen D., Rezvani, Niloofar, Wieseler, Julie, Hughes, Travis S., Landgraf, Kyle E., Chan, Stefanie, Fong, Stephanie, Phipps, Simon, Falke, Joseph J., Leinwand, Leslie A., Maier, Steven F., Yin, Hang, Rice, Kenner C., Watkins, Linda R.
Publicado em 2009