Evidence that opioids may have toll like receptor 4 and MD-2 effects

Opioid-induced proinflammatory glial activation modulates wide-ranging aspects of opioid pharmacology including: opposition of acute and chronic opioid analgesia, opioid analgesic tolerance, opioid-induced hyperalgesia, development of opioid dependence, opioid reward, and opioid respiratory depressi...

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Main Authors: Hutchinson, Mark R., Zhang, Yingning, Shridhar, Mitesh, Evans, John H., Buchanan, Madison M., Zhao, Tina X., Slivka, Peter F., Coats, Benjamen D., Rezvani, Niloofar, Wieseler, Julie, Hughes, Travis S., Landgraf, Kyle E., Chan, Stefanie, Fong, Stephanie, Phipps, Simon, Falke, Joseph J., Leinwand, Leslie A., Maier, Steven F., Yin, Hang, Rice, Kenner C., Watkins, Linda R.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2788078/
https://ncbi.nlm.nih.gov/pubmed/19679181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2009.08.004
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